Новости

6 декабря 2014 г. с огромным успехом прошла итоговая в этом году «Антитромботическая школа». В мероприятии приняли участие более 100 врачей и научных сотрудников из Москвы и Московской области.

13 октября 2014 г. прошел Всемирный День по борьбе с тромбозами. В нем приняло участие более 175 организаций и около миллиона человек по всему миру.

25 ноября 2014 года при поддержке Национального Научного Общества Воспаления в ФГБУ «ЦКБ с поликлиникой» УДП РФ состоялась первая конференция, организованная секцией "Лабораторная медицина"

Национальное Научное Общество Воспаления стало официальным партнером ISTH в проведении «Всемирного дня по борьбе с тромбозами», который будет проходить во всем Мире 13 октября 2014 года.

10 октября 2014 года при поддержке Национального Научного Общества Воспаления в ФГБУ «ЦКБ» УДП РФ состоится ставшая традиционной конференция «КАРДИОЛОГИЯ-2014.

1 сентября 2014 года Национальное Научное Общество Воспаления создало новую секцию «Лабораторная медицина».

Ведущими экспертами в области антитромботической терапии и лабораторной диагностики были освещены основные вопросы применения антитромботических средств в клинической практике.

Идеологической концепцией проекта является освещение актуальных вопросов введения пациентов страдающих сочетанной кардиореспираторной патологией.

В рамках заседания были обсуждены актуальные вопросы одинарной и двойной антитромбоцитарной терапии...

В мероприятии приняли участие более 130 человек из 5 регионов РФ. Присутствовали врачи из ФГБУ «ЦКБ с поликлиникой» УДП РФ, поликлиники №1и №3 УДП РФ.

14 марта 2014 года в г. Санкт-Петербург успешно прошел однодневный семинар для врачей «Антитромботические средства в клинической практике».

23 декабря 2013 г. состоялось заседания членов правления Национального Научного Общества Воспаления, в котором освещалась деятельность общества в 2013 г.

С 21 по 25 сентября 2013 года в г. Натале, Бразилия проходил 11 рабочий конгресс Всемирного Общества Воспаления и бразильской ассоциации иммунологов. На этом конгрессе приняли участие российские члены Национального Научного Общества Воспаления.Президент Всемирного Общества Воспаления Борис Варгафтиг выразил благодарность членам общества Воспаления из России за активное участие в конгрессе.

Introduction: Acute coronary syndrome (ACS) is caused by destabilization and rupture of atherosclerotic plaque in the coronary artery via mechanisms affecting leukocyte signaling, rolling, adhesion, extravasation and inflammation-promoting factors.

Objective and design: Insulin and inflammatory cytokines may be involved in equine laminitis, which might be associated with digital vascular dysfunction. 

Objective and design: As methylene blue (MB) has been recently proposed to preserve blood pressure in case of vasoplegic syndrome and shock, an entity directly related to systemic inflammation, we aimed to elucidate the effect of MB on the expression of adhesion-molecules in endothelial-cells.

Objective and design: The present study was aimed to evaluate the anti-inflammatory potentials of Vespa tropica (VT) venom and its isolated peptides. Effects of whole venom and its two peptides (Vt1512 and Vt1386) on lipopolysaccharide (LPS) challenged BV-2 murine microglial cells was evaluated.

Background: Thyroid disorders, including thyroid cancer and autoimmune thyroid diseases, have been closely associated with inflammation.

Objective and design: Previous studies indicate that endotoxin preconditioning may decrease the inflammatory response and alleviate intestinal mucosal damage caused by sepsis. 

Background: Anti-inflammatory cytokine effects of vagus nerve stimulation in sepsis syndromes are well established. Effects on immune cells are less clear. Therefore, we studied changes in peripheral and spleen leukocyte subsets in an endotoxic rat sepsis model.

<p><strong><span lang="en-US">Objective and design</span></strong><span lang="en-US"><strong>:</strong> Our study was designed to elucidate the precise molecular mechanisms by which sorbitol-modified hyaluronic acid (HA/sorbitol) exerts beneficial effects in osteoarthritis (OA).</span></p>

Objective: Immunodeficiency of end-stage renal disease (ESRD) is caused by several factors including uremic toxins and biocompatibility reactions due to the repeated hemodialysis (HD) procedure.

Introduction: Inflammaging is a phenomenon triggered by the conjunction of chronic repetitive and subclinical inflammation from external aggressors and internal inflammatory mechanisms due to the progressive degradation of systems such as the mitochondrial function. 

Nuclear factor kappa B (NF-κB) functions as a key regulator in the central nervous system and regulates the inflammatory pathway. There are two peaks of cerebral NF-κB activation after neonatal hypoxia–ischemia and subarachnoid hemorrhage.

Objective: Herpes simplex virus 1 (HSV-1) is regarded as an important underlying cause of Bell’s palsy, but the immunologic mechanism remains unknown.

Introduction: The leaves of Clerodendrum phlomidis L.f. have been used in the Indian traditional system of medicine to treat several inflammatory diseases and arthritis. 

The following summarises the plenary lectures of the ‘Bradykinin Symposium 2012’ held on 23−24 August 2012 at Charité-Universitätsmedizin Berlin, Germany. 

Objective: Inflammation and hypoxia activate the fractalkine (CX3CL1) receptor (CX3CR1)-related signaling pathway. Tumor necrosis factor alpha (TNFα) induces CX3CL1, influencing a mechanism of CX3CL1 autoregulation by CX3CR1 expression. 

Background: Because antileukotrienes may inhibit inflammation, it is plausible that montelukast administered for a long time could suppress skin wheal and flare reaction, and thus, it should be discarded prior to the tests. 

Objective and design: High mobility group box 1 (HMGB1) protein acts as a late mediator of severe vascular inflammatory conditions. Rutin (RT), an active flavonoid compound, is well known to possess potent antiplatelet, antiviral and antihypertensive properties.

Introduction: Previous studies found that neuron specific enolase promoter (Nse-BMP4) transgenic mice have increased expression of the nociceptive mediator, substance P and exaggerated local injury responses associated with heterotopic ossification (HO). 

Objective: Chronic HBV infection can lead to “immune tolerance” in asymptomatic carriers (ACs), “immune injury” in active chronic hepatitis (ACH) patients or “immune abnormality” in cirrhosis (Cir) and hepatocellular carcinoma (HCC) patients.

Objective: The aims of this review are to describe the present knowledge about YKL-40 protein, discuss its relation to liver fibrosis, and to look ahead at future perspectives of YKL-40 research.

Introduction: Asthma is one of the serious global health problems and cause of huge mortality and morbidity. It is characterized by persistent airway inflammation, airway hyperresponsiveness, increased IgE levels and mucus hypersecretion. Asthma is mediated by dominant Th2 immune response, causing enhanced expression of Th2 cytokines.

Objective: The coxsackie and adenovirus receptor (CAR) mediates the entry of coxsackievirus B (CVB) and adenovirus into host cells and is, therefore, a key determinant for the molecular pathogenesis of viral diseases such as myocarditis.

Objective and design: Atherosclerosis (ATH) is a chronic inflammatory disease that involves cascades of signaling events mediated by various effector proteins.

Objective: This study was conducted to investigate the role of stromal-derived factor-1 alpha (SDF-1α) in a secondary brain injury after traumatic brain injury (TBI) in rats, and to further elucidate its underlying regulatory mechanisms.

Objective and design: Variable tissue factor (TF) expression by human microvascular endothelial cells (HMVEC) may be regulated by two promoter haplotypes, distinguished by an 18-basepair deletion (D) or insertion (I) at −1,208. We sought to determine the relationship between these haplotypes and interleukin-1α (IL-1α)-induced TF expression in neonatal versus adult HMVEC.

Background: Ischemia–reperfusion injury (IRI) after lung transplantation remains a significant cause of morbidity and mortality. Lung IRI induces nitric oxide synthesis (iNOS) and reactive nitrogen species, decreasing nitric oxide bioavailability.

Objective: Disequilibrium of the cytokine network was reported to play an important role in the progression of chronic heart failure (CHF). Catechin exerts cardioprotection through treating many kinds of angiocardiopathy.

Objective and design: To evaluate the effects of simvastatin in peripheral blood mononuclear cell (PBMC) cytokines profiles and correlate with the disease state of rheumatoid arthritis (RA) patients.

Objective: The aim of the present study was to evaluate the levels and correlation of human S100A12 and high-sensitivity C-reactive protein (hs-CRP) in gingival crevicular fluid (GCF) and serum in chronic periodontitis (CP) subjects with and without type 2 diabetes mellitus (DM).

Objective and design: The sigma 1 (σ₁) receptor, which is widely distributed in the CNS in areas that are known to be important for pain control, may play a role in persistent pain characterized by the hypersensitivity of nociceptive transmission.

Objective: Expression and function of histamine H₄-receptor, an immunomodulatory receptor involved in inflammatory diseases, on murine macrophages, which are vital for immunity, were investigated.

<p><strong><span lang="en-US">Objective</span></strong><span lang="en-US"><strong>: </strong>We have previously demonstrated the efficient and time-dependent transvascular localization of Sialyl Lewis X (SLX)-liposomes to inflammatory sites, but the final target of the SLX-liposomes remained uncertain.</span></p>

<p><strong><span lang="en-US">Objective and design</span></strong><span lang="en-US"><strong>: </strong>TNF-</span>α<span lang="en-US"> neutralization is associated with increased mortality in mouse cecal ligation puncture (CLP) models. AZD9773 is an ovine polyclonal human TNF-</span>α<span lang="en-US"> immune Fab, with pharmacological properties that differ from previously studied anti-TNF-</span>α<span lang="en-US"> agents.</span></p>

Objective and design: This study was undertaken to evaluate the anti-inflammatory effect of the pure compound salicin on dextran sulfate sodium (DSS)-induced colitis in a mouse model and to quantify the major gut bacteria during the treatment.

Цель: Выяснить, участвует ли Нискарин через фосфатидилинозитол - 3 - киназу (PI3K) и РКВ-зивисимый путь в апоптозе нейронов, вызванном нейровоспалением.

Цель: Силибинин - главная активная молекула силимарина, извлеченная из Cirsium japonicum.

Цель: Система комплимента играет существенную роль в регулировании T-клеточных реакций. Однако, точный механизм, лежащий в основе C4-индуцируемой иммунотолерантности, остается неясным.

Цель: Переходный рецептор потенциал меластатин 7 (TRPM7) участвует в течении нормальных физиологических и патологических процессах.

<p><strong>Цель:</strong> Системы внутриносового применения для поставки препарата к месту воспаления занимают важное место в лечении астмы.</p>

Цель: Оценить эффект дефицита миелопероксидазы (MPO) на течение воспаления легких, вызванного нежизнеспособным сandida albicans (nCA).