Objective: Immunodeficiency of end-stage renal disease (ESRD) is caused by several factors including uremic toxins and biocompatibility reactions due to the repeated hemodialysis (HD) procedure.20:00 / 04.08.2014 подробнее Inflammaging: should this term be suitable for age related macular degeneration too?
Introduction: Inflammaging is a phenomenon triggered by the conjunction of chronic repetitive and subclinical inflammation from external aggressors and internal inflammatory mechanisms due to the progressive degradation of systems such as the mitochondrial function.20:00 / 04.08.2014 подробнее Biphasic activation of nuclear factor kappa B and expression of p65 and c-Rel after traumatic brain injury in rats
Nuclear factor kappa B (NF-κB) functions as a key regulator in the central nervous system and regulates the inflammatory pathway. There are two peaks of cerebral NF-κB activation after neonatal hypoxia–ischemia and subarachnoid hemorrhage.20:00 / 04.08.2014 подробнее The expression of IL-2 and IL-4 in CD4+ T cells from mouse lymph nodes and spleen during HSV-1-induced facial palsy
Objective: Herpes simplex virus 1 (HSV-1) is regarded as an important underlying cause of Bell’s palsy, but the immunologic mechanism remains unknown.20:00 / 04.08.2014 подробнее Anti-inflammatory and anti-arthritic effects of 3-hydroxy, 2-methoxy sodium butanoate from the leaves of Clerodendrum phlomidis L.f.
Introduction: The leaves of Clerodendrum phlomidis L.f. have been used in the Indian traditional system of medicine to treat several inflammatory diseases and arthritis.20:00 / 04.08.2014 подробнее Light and electron microscopic detection of inflammation-targeting liposomes encapsulating high-density colloidal gold in arthritic mice
<p><strong><span lang="en-US">Objective</span></strong><span lang="en-US"><strong>: </strong>We have previously demonstrated the efficient and time-dependent transvascular localization of Sialyl Lewis X (SLX)-liposomes to inflammatory sites, but the final target of the SLX-liposomes remained uncertain.</span></p>20:00 / 04.08.2014 подробнее Determination of the safety and efficacy of therapeutic neutralization of tumor necrosis factor-α (TNF-α) using AZD9773, an anti-TNF-α immune Fab, in murine CLP sepsis
<p><strong><span lang="en-US">Objective and design</span></strong><span lang="en-US"><strong>: </strong>TNF-</span>α<span lang="en-US"> neutralization is associated with increased mortality in mouse cecal ligation puncture (CLP) models. AZD9773 is an ovine polyclonal human TNF-</span>α<span lang="en-US"> immune Fab, with pharmacological properties that differ from previously studied anti-TNF-</span>α<span lang="en-US"> agents.</span></p>20:00 / 04.08.2014 подробнее Effect of salicin on gut inflammation and on selected groups of gut microbiota in dextran sodium sulfate induced mouse model of colitis
Objective and design: This study was undertaken to evaluate the anti-inflammatory effect of the pure compound salicin on dextran sulfate sodium (DSS)-induced colitis in a mouse model and to quantify the major gut bacteria during the treatment.20:00 / 04.08.2014 подробнее