Том 63 Номер 8, август 2014

Inflammation research

Inducible nitric oxide synthase inhibition reverses pulmonary arterial dysfunction in lung transplantation

Background: Ischemia–reperfusion injury (IRI) after lung transplantation remains a significant cause of morbidity and mortality. Lung IRI induces nitric oxide synthesis (iNOS) and reactive nitrogen species, decreasing nitric oxide bioavailability.

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Catechin ameliorates cardiac dysfunction in rats with chronic heart failure by regulating the balance between Th17 and Treg cells

Objective: Disequilibrium of the cytokine network was reported to play an important role in the progression of chronic heart failure (CHF). Catechin exerts cardioprotection through treating many kinds of angiocardiopathy.

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Expression of leukocyte adhesion-related glycosyltransferase genes in acute coronary syndrome patients

Introduction: Acute coronary syndrome (ACS) is caused by destabilization and rupture of atherosclerotic plaque in the coronary artery via mechanisms affecting leukocyte signaling, rolling, adhesion, extravasation and inflammation-promoting factors.

  20:00 / 05.08.2014 подробнее  
The effect of tumour necrosis factor-α and insulin on equine digital blood vessel function in vitro

Objective and design: Insulin and inflammatory cytokines may be involved in equine laminitis, which might be associated with digital vascular dysfunction. 

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Methylene blue modulates adhesion molecule expression on microvascular endothelial cells

Objective and design: As methylene blue (MB) has been recently proposed to preserve blood pressure in case of vasoplegic syndrome and shock, an entity directly related to systemic inflammation, we aimed to elucidate the effect of MB on the expression of adhesion-molecules in endothelial-cells.

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Vespa tropica venom suppresses lipopolysaccharide-mediated secretion of pro-inflammatory cyto-chemokines by abrogating nuclear factor-κ B activation in microglia

Objective and design: The present study was aimed to evaluate the anti-inflammatory potentials of Vespa tropica (VT) venom and its isolated peptides. Effects of whole venom and its two peptides (Vt1512 and Vt1386) on lipopolysaccharide (LPS) challenged BV-2 murine microglial cells was evaluated.

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Interleukins as markers of inflammation in malignant and benign thyroid disease

Background: Thyroid disorders, including thyroid cancer and autoimmune thyroid diseases, have been closely associated with inflammation.

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LPS preconditioning ameliorates intestinal injury in a rat model of hemorrhagic shock

Objective and design: Previous studies indicate that endotoxin preconditioning may decrease the inflammatory response and alleviate intestinal mucosal damage caused by sepsis. 

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Effects of anti-inflammatory vagus nerve stimulation in endotoxemic rats on blood and spleen lymphocyte subsets

Background: Anti-inflammatory cytokine effects of vagus nerve stimulation in sepsis syndromes are well established. Effects on immune cells are less clear. Therefore, we studied changes in peripheral and spleen leukocyte subsets in an endotoxic rat sepsis model.

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Sorbitol-modified hyaluronic acid reduces oxidative stress, apoptosis and mediators of inflammation and catabolism in human osteoarthritic chondrocytes

<p><strong><span lang="en-US">Objective and design</span></strong><span lang="en-US"><strong>:</strong> Our study was designed to elucidate the precise molecular mechanisms by which sorbitol-modified hyaluronic acid (HA/sorbitol) exerts beneficial effects in osteoarthritis (OA).</span></p>

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